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Internship Situation Analysis Survey Report
(College of Health Sciences, Makerere University, 2022-05)
Internship is a mandatory pre-registration training required for licensure of doctors in Uganda. During the internship, medical workers acquire practical skills, attitudes and knowledge critical for them to work without ...
Breast Cancer Molecular Subtype Prevalence and Commonly Mutated Genes in Triple Negative Breast Cancer in Uganda
(Makerere University, 2022-11-25)
Breast cancer is the second commonest cancer in women in Uganda, accounting for about 21% of all cancer related mortality in women in Uganda. An estimated 35-36% of all breast cancer patients in Uganda have triple negative ...
Aspergillus sensitisation and asthma in Uganda
(Makerere University, 2022-10-31)
Background:
Asthma is one of the neglected diseases in Africa and occurs at a high prevalence. Allergic fungal diseases have been reported to complicate asthma progression and treatment outcomes. Aspergillus fumigatus ...
Insights into genomic variations between Mycobacterium tuberculosis compartmentalized in the lungs and blood of HIV-infected individuals in Uganda
(Makerere University, 2022-08-19)
Introduction: Mycobacterium tuberculosis (MTB), particularly clinical strains present a
genomic diversity that ranges from several single nucleotide polymorphisms (SNPs) to insertions
and deletions (INDELS). This study ...
Effect of baseline immune status on the antibody responses to Hepatitis B vaccination among adults
(Makerere University, 2022-11-30)
Background; Hepatitis B virus (HBV) causes vaccine-preventable Hepatitis B disease. However, the immune response to the Hepatitis B vaccine varies, and 5 – 15% of vaccine recipients do not produce sufficient antibodies. ...
Genotypic and phenotypic characterization of HIV-1 transmitted/founder viruses and their effect on cytokine profiles and disease progression among acutely infected Ugandans
(Makerere University, 2022)
Virus-host interaction early after transmission elicit changes that are known to impact the course of the infection and clinical outcome. The nature of the virus that initiates the infection seems to play a key role. For ...
Insights into genomic variations between Mycobacterium tuberculosis compartmentalized in the lungs and blood of HIV-infected individuals in Uganda
(Makerere University, 2022)
Introduction: Mycobacterium tuberculosis (MTB), particularly clinical strains present a genomic diversity that ranges from several single nucleotide polymorphisms (SNPs) to insertions and deletions (INDELS). This study ...
Monitoring antibacterial use in children under five years in rural communities of Northern Uganda
(Makerere University, 2022)
Background: Acute respiratory tract infections (ARIs) and diarrhea are leading causes of childhood morbidity and mortality in low- and middle-income countries (LMICs), the burden is high among children under five years of ...
Colistin resistance among gram negative rods carried in the intestinal tract of patients admitted in the ICU of Mulago National Referral Hospital
(Makerere University, 2022-04)
Background: The limited options for treatment of infections caused by MDR or XDR bacteria prompted the reintroduction of colistin, which coupled with extensive use in food-producing animals is driving increasing resistance ...
Extended automated NGS pipeline for reproducible analysis of mosquito genomes
(Makerere University, 2022-11)
Over the past decade, the decreasing costs of sequencing have facilitated the agnostic interrogation of vector genomes, giving access to an ever-expanding volume of high quality genomic and transcriptomic data. Today, the ...