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Treatment interruptions predict resistance in HIV-positive individuals purchasing fixed-dose combination antiretroviral therapy in Kampala, Uganda
(Lippincott, Williams & Wilkins, 2007)
Objective: To evaluate adherence, treatment interruptions, and outcomes in patients purchasing antiretroviral fixed-dose combination (FDC) therapy. Design: Ninety-seven participants were recruited into a prospective 24-week ...
A novle polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single dose efavirenz population pharmacokinetics in Ugandans
(Wiley-Blackwell, 2009)
AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated population pharmacokinetic/pharmacogenetic model and investigate the impact of genetic variations, ...
Strategies to optimize HIV treatment outcomes in resource-limited settings
(Permanyer Publications, 2009)
Although the availability of antiretroviral therapy has increased rapidly to reach over three million people in low- and middle-income countries, coverage remains low as only 31% of people in need were receiving antiretroviral ...
The effect of AIDS defining conditions on immunological recovery among patients initiating antiretroviral therapy at Joint Clinical Research Centre, Uganda
(BioMed Central, 2009-07-24)
Background: Many HIV-infected patients only access health care once they have developed advanced symptomatic disease resulting from AIDS Defining Conditions (ADCs). We carried out a study to establish the effect of ADCs ...
Effect of home based water chlorination and safe storage on diarrhea among persons with human immonodeficiency virus in Uganda.
(American Society of Tropical Medicine and Hygiene, 2005)
Diarrhea is frequent among persons infected with human immunodeficiency virus (HIV) but few interventions are available for people in Africa. We conducted a randomized controlled trial of a home-based, safe water intervention ...
The international HIV dementia scale: a new rapid screening test for HIV dementia.
(Lippincott Williams & Wilkins, 2005)
Objective: HIV dementia is an important neurological complication of advanced HIV infection. The use of a cross-cultural screening test to detect HIV dementia within the international community is critical for diagnosing ...
Strengthening primary care: addressing the disparity between vertical and horizontal investment.
(Royal College of General Practitioners, 2008-01)
Recently we have seen an unprecedented increase of financial support to improve health care in developing countries estimated at 26% between 1997 and 2002, from $6.4 billion to $8.1 billion. While the magnitude of such an ...
Comparative studies on orphans and non-orphans in Uganda
(Center for International Health and Development, 2004-10)
There are now in Uganda more than two million orphans, i.e. children under 18 years old who have lost one or both of their parents. Roughly one in every five children is an orphan and one in every four households in the ...
The prevalence and associated factors of trichomonas vaginalis among women attending antenatal clinic in mulago Hospital.
(2005-06)
Introduction: Trichomonas vaginalis is emerging as the most common sexually transmitted disease. It is associated with a number of obstetrical complications such as preterm delivery, low birth weight and premature rupture ...
Voluntary HIV counselling and testing among men in rural western Uganda: Implications for HIV prevention
(BioMed Central, 2008-07-30)
Background: Voluntary HIV counselling and testing (VCT) is one of the key strategies in the prevention and control of HIV/AIDS in Uganda. However, the utilization of VCT services particularly among men is low in Kasese ...