College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 2962
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Retention in care, viral suppression and factors associated with viral non-suppression among refugee adolescents infected with HIV at Kyangwali Refugee Settlement in Kikuube District, Uganda
(Makerere University, 2023)Introduction: Compared to HIV positive non-refugee adolescents, refugee adolescents are generally less likely to receive antiretroviral therapy, and access to the drugs is often inconsistent (UNHCR, 2015). This study aimed ... -
Investigating Metabolic and Molecular Ecological Evolution of Opportunistic Pulmonary Fungal Coinfections: Protocol for a Laboratory-Based Cross-Sectional Study
(JMIR, 2023-12)Background: Fungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms and microbiome ... -
Plasmodium falciparum genetic diversity and multiplicity of infection based on msp‑1, msp‑2, glurp and microsatellite genetic markers in Sub-Saharan Africa: a systematic review and meta-analysis
(BMC, 2024)Background In sub-Saharan Africa (SSA), Plasmodium falciparum causes most of the malaria cases. Despite its crucial roles in disease severity and drug resistance, comprehensive data on Plasmodium falciparum genetic ... -
A comparison of frequencies and function of myeloid derived suppressor cells (MDSCS) IN TB/HIV co-infected and HIV mono-infected individuals in Uganda
(Makerere University, 2023)Background Myeloid-derived suppressor cells (MDSC) encompass a subset of myeloid cells, which suppress both innate and adaptive immune functions. These cells negatively regulate the immune function either by arginine ... -
Sero-antigen prevalence of lymphatic filariasis and risk factors of podoconiosis in Busiriba Sub-county, Kamwenge District, Southwestern Uganda, August–September 2018
(BMC, 2024)Objective Given the neglected nature of filariasis, especially in Uganda where data are scarce, this cross-sectional study aimed to determine the sero-antigen prevalence of lymphatic filariasis and risk factors associated ... -
Incidence and etiology of catheter associated urinary tract infection among admitted patients at Kabale Regional Referral Hospital, South Western Uganda
(Scientific Research Publishing, 2019)Introduction: Catheter Associated Urinary Tract Infection is the most common hospital acquired infection worldwide. Urinary Tract Infections among catheterised patients are on rise regardless of antibiotic use and this is ... -
Clindamycin resistance among methicillin resistant staphylococcus aureus isolated from human and respective household swine in greater Kabale Region—South Western Uganda
(Scientific Research Publishing, 2019)Introduction: S. aureus is recognized as the common cause of nosocomial and community-acquired infections. Macrolide-Lincosamide-Streptogramin B (MLSB) is thought to be alternative therapies against MRSA infections. Clindamycin ... -
Functioning and control of phagocytosis
(IntechOpen, 2023)Phagocytosis is a very complex and versatile process that contributes to immunity through a series of events that is it’s sometimes referred to the Come and Eat me process. Due to the recognition ingestion and digestion ... -
Laboratory Diagnosis of Candidiasis
(IntechOpen, 2022-08)The burden of Candidiasis continues to increase and so does the Candida species. Although Candida species are closely similar phenotypically, they differ from each other in terms of epidemiology, genetic characteristics, ... -
Diversity and distribution of Spa Types among Methicillin resistant staphylococcus aureus isolated from humans and livestock in Kabale District - South Western Uganda
(Journal of Veterinary Health Science, 2022)Background: S. aureus is a skin and mucosal bacterial commensal of both humans and animals which has evolved as an important pathogen implicated to cause various infections. High levels of antibiotic use have resulted into ... -
Prevalence, associated factors and management of suspected adverse drug reactions among patients taking dolutegravir in Uganda
(Makerere University, 2024-04-30)In 2018, Uganda introduced a newer first-line Antiretroviral Therapy (ART) medicines approved by the World Health Organization (WHO)-Dolutegravir (DTG). The ambitious roll-out of these HIV treatment strategies was not ... -
Level of utilization and factors associated with completion of maternal health care services along care continuum by women attending OPD at Nebbi General Hospital
(Makerere University, 2024-05)Introduction: A Continuum of maternal health services throughout pregnancy, childbirth, and postnatal care is an effective strategy for reducing maternal and newborn mortality. A low proportion of mothers achieve a complete ... -
Knowledge and Practices in difficult airway management among anaesthesia providers in Uganda: A cross-sectional study
(Makerere University, 2023)Introduction: Difficult airway scenarios can occur in the operating theatre as an anticipated or unanticipated event. Knowledge on airway management coupled with preparation, planning, communication and teamwork are ... -
Timing and quality of antenatal care for adolescent mothers attending maternal and child health clinics at two high volume health facilities in Nakawa Division Kampala District,Uganda
(Makerere University, 2023)Background: Maternal health services including antenatal care have been shown to improve reproductive health outcomes of pregnant adolescents. However, full utilisation of antenatal care (ANC) services among pregnant ... -
Treatment outcomes and factors associated with non-cure of tuberculosis in Wakiso district
(Makerere University, 2018)Background: Tuberculosis (TB) threatens public health all over the world. Uganda has not achieved the international targets for cure rate, treatment completion and default rate. Wakiso district in central part of the country ... -
Prevalence of cesarean section, outcomes and related factors among adolescent mothers (10-19 years) in Mayuge and Kamuli Districts
(Makerere University, 2023)Introduction Cesarean section is a potentially lifesaving intervention. However, it carries life-threatening health complications. There are limited studies on cesarean section rates and related factors among adolescent ... -
Health-related quality of life among adult patients with cancer in Uganda – A cross-sectional study
(Taylor & Francis, 2024)Objectives: The study aimed to investigate the prevalence and factors associated with poor health-related quality of life in adults with cancer in Uganda. Methods: This cross-sectional study surveyed 385 adult patients ... -
Detection of clinically relevant respiratory viruses and their temporal dynamics in sputum of tuberculosis patients on anti-TB drugs at Naguru Hospital, Kampala, Uganda
(Makerere University, 2024)Background Tuberculosis is one of the leading infectious causes of death in the world, with nearly 10 million new cases diagnosed each year, resulting into an estimated 1.3 million deaths(1). The relationship between M. ... -
Factors associated with incomplete COVID-19 vaccination among healthcare workers in Kampala Capital City Health Facilities. An explanatory sequential mixed methods study
(Makerere University, 2024)Introduction: Health workers involved in rapid response to viral infectious disease outbreaks like Ebola, Marburg among others are almost certainly at an increased risk of acquiring infection compared to the public. Like ... -
Antimicrobial stewardship practices and quality of antibacterial use in children under five and women in labour with obstetric risk factors in selected health facilities in Uganda
(Makerere University, 2024)Introduction Bacterial infections are a leading cause of morbidity and mortality in Ugandan hospitalised children under the age of five. Disparities exist in using antibacterial agents to treat bacterial infections at ...