College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3317
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Pharmacokinetic and pharmacodynamic considerations of rifamycin antibiotics for the treatment of tuberculosis
(Taylor and Francis, 2019)Tuberculosis (TB) treatment was revolutionized in 1965 with the discovery of rifamycins by Sensi et al. [1]. With the introduction of rifamycins, treatment duration drastically decreased from 18 to 6 months [2]. Rifamycins, ... -
Evaluation of effective lactogenic doses of Moringa oleifera ethanol extract in Swiss Albino Rats
(Makerere University, 2022)Introduction Breastfeeding is a foundation of child development health and survival, women with insufficient milk use Moringa oleifera in enhancing breast milk without standard doses and dosage forms. Literature review. ... -
Factors associated with in-hospital mortality of neonates with anorectal malformations at Mulago National Referral Hospital
(Makerere University, 2025)Background Anorectal malformation is a common disease entity among neonates presenting to pediatric surgery units in Uganda. The optimal care for these babies is compromised by gaps in several of the pillars of the ... -
Predictive role of neurofilament light protein in neurological and mental health outcomes following non-severe trauma among adults: A prospective cohort study at Mulago National Referral Hospital
(Makerere University, 2025)INTRODUCTION- Traumatic Brain Injury (TBI) is a major risk for neurological and neuropsychological disorders. Neuroaxonal damage is a major determinant of outcomes of TBI, and Neurofilament Light chain protein (NfL), a ... -
Prevalence, etiology and computed tomography finding in patients with traumatic brain injury at Mulago National Referral Hospital: A cross sectional study
(Makerere University, 2025)Background: Traumatic brain injury (TBI) refers to brain damage following trauma to the head. It is one of the leading causes of morbidity and mortality in the world. The incidence of TBI is a growing burden due to increasing ... -
Prevalence of multi-drug resistant UTIs and antibiotic sensitivity profiles amongst male patients with bladder outlet obstruction: A cross-sectional study
(Makerere University, 2025)Background: Antimicrobial resistance (AMR) is a rapidly emerging global problem with multidrug resistant (MDR) urinary tract infections (UTIs) complicating treatment, particularly in low and middle-income countries (LMICs). ... -
Prosthetic fitting and associated factors among lower limb amputees at Mulago Hospital
(Makerere University, 2025)Background: Lower limb amputations are a significant global health challenge, with Uganda experiencing a notable burden. Despite the essential role of prosthetic fitting in rehabilitation, disparities in access and prosthetic ... -
Prevalence, correlates, and predictive value of high-risk human papillomavirus mRNA detection in a community-based cervical cancer screening program in Western Uganda
(BMC, 2019)Background: New strategies are needed to combat the high incidence of cervical cancer in resource-limited settings such as sub-Saharan Africa. Screening for high-risk human papillomavirus (hrHPV) DNA is sensitive for ... -
Longer-term effectiveness of protease-inhibitor-based second line antiretroviral therapy in four large sub-Saharan African clinics
(Elsevier, 2019)Objectives: Data on the longer-term effectiveness of second line combination antiretroviral therapy (ART) in sub-Saharan Africa (SSA) are lacking. We sought to assess the probability and determinants of 2nd line ART ... -
Severity of post - operative knee stiffness and associated factors after surgical fixation of knee osseous injuries among adults at Mulago National Referral Hospital
(Makerere University, 2025-05)Background: Knee stiffness following surgical fixation of knee osseous injuries is a common and potential complication of surgery and rehabilitation with a global incidence of 4% to 38%. Even with the currently recommended ... -
The 14-day incidence and risk factors of gastrointestinal anastomotic leak among adult patients in Mulago Hospital, a prospective cohort study
(Makerere University, 2025)Background: Anastomotic leak is one of the most feared complications following gastrointestinal (GI) anastomotic surgery. It increases morbidity and mortality of patients undergoing GI surgery. Globally, the frequency of ... -
Prevalence and factors associated with hypertension among female nurses in private healthcare facilities in Jinja City
(Makerere University, 2024)Introduction: Hypertension affects 1.3 billion people globally and is predicted to rise to 1.56 billion by 2025, influenced by urbanization, sedentary lifestyles, and dietary shifts. Despite being essential to Uganda's ... -
Experiences of adult patients with cancer at a specialized cancer care facility in Uganda
(Wolters Kluwer Health Inc., 2025)Background: The experiences of adult cancer patients in low-income countries regarding health care and infrastructure are largely undocumented. This study aimed to describe the experiences of adult men and women receiving ... -
Adult patients with cancer in Uganda: validation of the tool, health-related quality of life, and patient experiences
(Makerere University, 2025)Background: This study aimed to assess the validity and reliability of the Luganda version of the tool used to measure health-related quality of life (HRQoL), specifically the European Organisation for Research and Treatment ... -
Prevalence and factors associated with pre-operative delays among neurotraumatic patients at Mulago National Referral Hospital: a cross-sectional study
(Makerere University, 2025)Introduction Neurotraumatic emergencies affect more than 10 million people globally with majority of them from sub-Saharan. Neurotraumatic emergencies present a challenge in emergency surgical care, demanding quick and ... -
An assessment of organisational knowledge management for health: a case study of a non-governmental organisation in Kampala, Uganda
(Makerere University, 2023)Knowledge management is a discipline that promotes an integrated approach to identifying, capturing, evaluating, retrieving, and sharing information assets. Knowledge management involves people, processes, and technology ... -
Prevalence and grading of meconium-stained amniotic fluid plus associated puerperal sepsis within 7 days at Kawempe National Referral Hospital.
(Makerere University, 2024)Background: Meconium-stained amniotic liquor remains both a maternal and neonatal health challenge globally as it is associated with higher rate of caesarean delivery, increased need for neonatal resuscitation, puerperal ... -
Short term outcomes of unstable pelvic fractures in adults treated at Mulago National Referral Hospital
(Makerere University, 2025)Introduction Pelvic fractures are perhaps the most severe & life-threatening musculoskeletal injuries, constituting about 1.5%–3% of all skeletal injuries. Despite their severity, unstable pelvic fractures can yield ... -
Adult patients with cancer in Uganda : validation of the tool, health-related quality of life, and patient experiences
(Makerere University, 2025)Background: This study aimed to assess the validity and reliability of the Luganda version of the tool used to measure health-related quality of life (HRQoL), specifically the European Organization for Research and Treatment ... -
Depressive and anxiety symptoms predict sustained quality of life deficits in HIV-positive Ugandan adults despite antiretroviral therapy
(Lippincott, 2016)The impact of psychosocial status at onset of antiretroviral therapy on changes in quality of life (QOL) and subjectively rated health (SRH) among adults on ART in resource-limited settings is poorly understood. Therefore, ...