College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3371
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Characterization of transcriptome diversity of invasive ductal carcinoma tissue from individuals of different ethnicities and ages
(Makerere University, 2023)Breast cancer is a heterogeneous disease, and its incidence and prognosis are influenced by various factors including age and ethnicity. Consequently, tumors from individuals of different age groups and ethnicities may ... -
New manual quantitative polymerase chain reaction assay validated on tongue swabs collected and processed in Uganda shows sensitivity that rivals sputum-based molecular tuberculosis diagnostics
(Oxford Academic, 2024)Background: Sputum-based testing is a barrier to increasing access to molecular diagnostics for tuberculosis (TB). Many people with TB are unable to produce sputum, and sputum processing increases assay complexity and cost. ... -
Knowledge of cardiovascular disease risk factors among diabetic patients attending the non-communicable disease clinic at Tororo General Hospital
(Makerere University, 2024)Background: Diabetic patients have a threefold risk of developing cardiovascular disease complications compared to the general population. According to world health organization diabetes mellitus accounts for over 20% of ... -
Prevalence of depression and associated factors among school-going adolescents with hearing impairment in Kampala District, Uganda
(Makerere University, 2025)Background: Depression remains one of the most common and disabling mental disorders among adolescents globally. Well as its burden has been widely studied, little is still known about how it affects school-going adolescents ... -
Maternal near miss at Kawempe National Referral Hospital: risk factors and immediate perinatal outcomes
(Makerere University, 2025)Introduction: The maternal near misses (MNM) are used as a proxy for, and exceeds maternal deaths by upto 20 times, yet studying them is more advantageous at improving the quality of maternal and perinatal care. They have, ... -
Dyslipidaemias in women using hormonal contraceptives: a cross sectional study in Mulago Hospital Family Planning Clinic, Kampala, Uganda
(BMJ, 2018)Objective To determine the prevalence and factors associated with dyslipidaemias in women using hormonal contraceptives. Design Cross-sectional study. Setting Mulago Hospital, Kampala, Uganda Participants Three hundred ... -
Overcoming challenges of managing chronic obstructive pulmonary disease in low-and middle-income countries
(Taylor and Francis, 2024)Introduction: Chronic obstructive pulmonary disease (COPD) ranks among the top three global causes of death, with 90% of fatalities concentrated in low- and middle-income countries (LMICs). The projected rise in COPD burden, ... -
Prevalence of perceived occupational injuries and associated factors among factory workers in Mogadishu, Somalia
(Makerere University, 2024)Introduction: Occupational injuries are a significant public health concern, particularly in developing countries where the burden is 10 to 20 times higher than in industrialized nations. In Somalia, factory work is ... -
Prevalence of chronic kidney disease among young people living with HIV in Sub Saharan Africa: A systematic review and meta-analysis
(PLoS ONE, 2024)Background Globally, the prevalence of chronic kidney disease (CKD) is increasing among young people living with HIV (YPLHIV), with inconsistent estimates. Aggregated data on the prevalence of CKD are needed in sub-Saharan ... -
Comparison of the prevalence and associated factors of chronic kidney disease diagnosed by serum creatinine or cystatin C among young people living with HIV in Uganda
(BMC, 2024)Introduction Young people living with HIV (YPLHIV) are at increased risk of developing chronic kidney disease (CKD) which is associated with high mortality and morbidity. Early diagnosis is important to halt progression. ... -
Sex differences in the prevalence of geriatric syndromes among older people living with HIV attending an urban outpatient clinic in Kampala, Uganda
(Dovepress, 2024)Background Older people living with HIV (PLHIV) are at high risk of developing geriatric syndromes. Data on geriatric syndromes among older PLHIV in sub-Saharan Africa are scarce. We examined sex differences in the ... -
Feasibility and factors affecting the diagnostic accuracy of a self-administered PHQ-9 for depression screening at Mukono Church of Uganda Hospital HIV Clinic
(Makerere University, 2025)Background: Comorbid depression is three times more prevalent among people living with HIV in Uganda, yet its diagnosis is still a challenge due to multiple factors such as inadequate health care work force that results ... -
The prevalence and factors associated with depression among undergraduates at Makerere University who have experienced intimate partner violence
(Makerere University, 2025)Background: Depression among university students is a growing public health concern, particularly in those who have experienced intimate partner violence (IPV). Understanding the prevalence and associated factors is crucial ... -
Career development for infection and immunity research in Uganda: a decade of experience from the Makerere University - Uganda Virus Research Institute research and training programme
(African Academy of Science, 2020)Background: The Makerere University/Uganda Virus Research Institute (UVRI) Centre of Excellence for Infection & Immunity Research and Training (MUII) is a collaborative programme supporting excellence in Infection and ... -
Intention to use immediate postpartum contraception and associated factors amongst mothers delivering from Kisenyi and Kawaala HC IVs
(Makerere University, 2025)Background:. The global prevalence of unintended pregnancies is about 41%, and 40% in low and middle-income countries. A study in Yumbe district indicated the prevalence of short birth intervals of 52.4%, from which 12% ... -
Frequency, course, outcomes and factors associated with delirium among adult patients admitted to Uganda Cancer Institute
(Makerere University, 2025)Background: Delirium is a neurocognitive disorder that commonly affects patients with cancer. Among patients with cancer admitted to oncology units, the prevalence varies from 18% to 33% and the incidence varies from 3.5% ... -
The Clinical Presentation and Factors Associatedwith Disease Severity of Rheumatoid Arthritis inUganda: A Cross-Sectional Study
(2022)Background Rheumatoid arthritis (RA) is a chronic, debilitating disease that leads to joint destruction and disability if left untreated. Few studies on RA have been conducted in Uganda, and there is limited information ... -
Prevalence of arps10, fd, pfmdr-2, pfcrt and pfkelch13 gene mutations in Plasmodium falciparum parasite population in Uganda
(PloS ONE, 2022)In Uganda, Artemether-Lumefantrine and Artesunate are recommended for uncomplicated and severe malaria respectively, but are currently threatened by parasite resistance. Genetic and epigenetic factors play a role in ... -
Identification of pathogen genomic differences that impact human immune response and disease during cryptococcus neoformans infection
(American Society for Microbiology, 2019)Patient outcomes during infection are due to a complex interplay between the quality of medical care, host immunity factors, and the infecting pathogen’s characteristics. To probe the influence of pathogen genotype on human ... -
Assessment of parasite clearance following treatment of severe malaria with intravenous artesunate in Ugandan children enrolled in a randomized controlled clinical trial
(BMC, 2018)Background Malaria control largely depends on availability of highly efficacious drugs, however, over the years, has been threatened by emergence of drug resistance. It is, therefore, important to monitor the impact of ...