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Coverage and effect of intensive adherence counseling on viral load suppression in a public HIV Care Center, Kampala, Uganda: A mixed methods retrospective study January 2015 to October 2018
(Makerere University, 2022-02)
Background: Intensive adherence counseling (IAC) is fundamental to enhance adherence and increase durability of ART regimens among ART treated unsuppressed people living with HIV (PLWH). This study evaluated coverage, ...
Simulation of clonal expansion and latent HIV reservoir size prediction using machine learning in virally suppressed individuals in Uganda
(Makerere University, 2022-07)
Background: HIV can survive as pro-viruses that do not undergo transcription mostly within resting memory CD4+ T cells despite prolonged antiretroviral therapy (ART). This Latent Viral Reservoir (LVR) has an extremely long ...
Isoniazid preventive therapy completion and factors associated with non-completion among patients on antiretroviral therapy at Kisenyi Health Centre IV, Kampala, Uganda
(Makerere University, 2022-08)
Introduction: Isoniazid preventive therapy is given to people living with HIV to reduce the risk of active tuberculosis. However, treatment completion remains sub-optimal among those that are initiated. This study aimed ...
Test and treat policy: Effect on ART initiation and retention and health system barriers and facilitators to implementation in AHF Uganda Cares Clinics in Central Uganda
(Makerere University, 2022-05)
Background: The ‘Test and Treat’ policy was introduced by the WHO in 2015 as a measure to extend the benefits of ART to all HIV positive patients and, in a bid to enable the achievement of the UNAIDS 95-95-95 2030 ...
Risky sexual behaviour and associated factors among HIV positive people on ART at Uganda Cares - St Balikuddembe Clinic : a cross sectional study
(Makerere University, 2022)
Introduction: ART has enabled PLHIV to live as close to normal lives as the rest of the global population. The initial anti-retroviral drugs in a way deterred individuals from risky sexual behaviors because data didn’t ...
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
(AOSIS, 2022)
Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to achieve global Sustainable ...
Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)
Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one
of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as
it jeopardizes the efforts to ...
Suspected adverse drug reactions of isoniazid preventive therapy in HIV-positive patients at three regional hospitals: prevalence, associated factors, management and reporting
(Makerere University, 2021-11)
Background
Tuberculosis (TB) is the 10th leading cause of death globally and the leading cause of death from a single infectious agent among people living with HIV (PLHIV). Uganda is among the 30 high burden TB countries ...
Prevalence and factors associated with dyslipidemia among adult patients on dolutegravir based antiretroviral regimen at Mengo Hospital, A cross-sectional study
(Makerere University, 2022-12)
Introduction: Dolutegravir (DTG) based anti-retroviral therapy (ART) regimen has been rolled out in Uganda as the preferred first- and second-line treatment option in the management of Human Immunodeficiency Virus (HIV). ...
Dual contraceptive utilization and associated factors among women living with the Human Immunodeficiency Virus (HIV) at Kawempe National Referral Hospital, Kampala Uganda
(Makerere University, 2022-12)
Introduction: Dual contraceptive utilization (DCU) maximizes the prevention of unintended pregnancies and sexually transmitted infections including HIV infection. In Uganda DCU among women living with HIV (WLHIV) is low. ...