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Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisinin combination therapy: complexity of infection during short-term culture and characterization of in vitro sensitivity in Kampala Uganda
(Makerere University, 2010)
Background: Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant ...
Fetal haemoglobin and disease severity in sickle cell anaemia patients attending the sickle cell clinic in Mulago Hospital
(2010)
Background: Sickle cell anaemia (SCA) is a major problem in Uganda; it is estimated to contribute about 15% of paediatric admissions and 10% mortality in children at Mulago hospital. Fetal haemoglobin (HbF) level is one ...
HIV-subtype A is associated with poorer neuropsychological performance compared with subtype D in antiretroviral therapy-naive Ugandan children
(Lippincott Williams & Wilkins, 2010)
Background: HIV-subtype D is associated with more rapid disease progression and
higher rates of dementia in Ugandan adults compared with HIV-subtype A. There are no
data comparing neuropsychological function by HIV subtype ...
NeuroAIDS in Africa
(Informa Healthcare, 2010)
In July 2009, the Center for Mental Health Research on AIDS at the National
Institute of Mental Health organized and supported the meeting “NeuroAIDS
in Africa.” This meeting was held in Cape Town, South Africa, and ...
Social Networks of PLHA in Uganda: Implications for Mobilizing PLHA as Agents for Prevention
(Springer, 2010-05)
The objective of this study was to describe the social networks of people living with HIV/AIDS (PLHA) and explore the implications social network characteristics might have for mobilizing PLHA as prevention agents. Thirty-nine ...
Challenges faced by health workers in providing counselling services to HIV-positive children in Uganda: a descriptive study
(BioMed Central, 2010)
Background: The delivery of HIV counselling and testing services for children remains an uphill task for many health workers in HIV-endemic countries, including Uganda. We conducted a descriptive study to explore the ...
Bronchoscopy is useful for diagnosing smear-negative tuberculosis in HIV-infected patients
(European Respiratory Journal, 2010)
Influence of M. tuberculosis lineage variability within a clinical trial for pulmonary tuberculosis
(PLoS ONE, 2010)
Abstract Recent studies suggest that M. tuberculosis lineage and host genetics interact to impact how active tuberculosis presents clinically. We determined the phylogenetic lineages of M. tuberculosis isolates from ...
Thyroid hormones profile in students of Makerere College of Health
(Tanzania Health Users' Trust Fund, 2010-01)
Serum concentrations of thyroxine (T4), triiodothyronine (T3) and Thyroid Stimulating Hormone (TSH) are used to assess thyroid function. It is recommended that each laboratory or hospital should establish its own reference ...
Chlorproguanil-dapsone for treating uncomplicated malaria (Review)
(JohnWiley & Sons, 2010)
Background In Africa, malaria is often resistant to chloroquine and sulfadoxine-pyrimethamine. Chlorproguanil-dapsone is a potential alternative. Objectives To compare chlorproguanil-dapsone with other antimalarial drugs ...