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HIV-1 co-receptor usage of contemporary transmitted/ founder viruses in Uganda
(Makerere University, 2022-12-21)
Background: Globally, HIV remains a global public health threat despite the serious efforts to stop it using combination antiretroviral therapy. This could be attributed to the lack of preventative and curative treatment ...
Hepatitis B in Uganda: Transmission and prevention strategies among infants and HIV-infected adults
(Makerere University, 2022-10)
This thesis is focused on hepatitis B virus (HBV) transmission and prevention in the setting of human immune deficiency syndrome (HIV) infection. HBV is common among HIV-infected persons in part due to shared modes of ...
Prevalence and factors influencing suboptimal adherence to dolutegravir-based regimens among adult patients at Joint Clinical Research Center, Lubowa
(Makerere University, 2022-12)
Background: An estimated 37.7 million people are living with HIV globally with the majority being in sub-Saharan Africa. There is a need to address suboptimal adherence to prevent dolutegravir resistance in order to maintain ...
Patient single nucleotide polymorphisms assiocated with Mycobacterium tuberculosis genotypes in Ugandan population
(Makerere University, 2022-12)
Uganda is one of the 30 World Health Organization-designated countries with a high burden of TB/HIV, with three main dominant genotypes that cause tuberculosis. Recent studies have shown that the M. tuberculosis Uganda ...
Acceptability of SMS reminders as an HIV PREP adherence support tool and associated factors among adolescent girls and young women in Mukono District
(Makerere University, 2022-12)
Background: Young Women in Uganda contributed 29% of new HIV infections despite representing only 10% of the total population and are priority beneficiaries of PrEP, yet they have been found to have low adherence. SMS ...
Uptake and determinants of HIV retesting among high risk seronegative persons in fishing communities of Kasenyi Landing Site – Central Uganda
(Makerere University, 2023-01)
Background: Whereas the incidence of HIV has gradually reduced over the past 20 years, promotion of HIV preventive measures such as periodic retesting amongst high-risk populations has become a global priority. WHO recommends ...
Discontinuation of pre-exposure prophylaxis and associated factors among sex workers attending the most at Risk Population Clinic, Mulago Hospital
(Makerere University, 2022-12)
Background
Pre-exposure prophylaxis (PrEP) uptake and retention rates in clinical trials have been well characterized. However, little is known about PrEP discontinuation in routine public health settings in developing ...
Correlation of plasma HIV-1 p24 antigen levels with viral load in samples of HIV positive patients on ART in Uganda
(Makerere University, 2022-12)
Globally, a total of 38.0 million people living with HIV, of which 1.7 million people became newly infected with HIV in 2019. Additionally, an average of 690,000 people died from AIDS-related illnesses in 2019, and 26 ...
Utilization of dual protection methods of modern family planning by women aged 15-49 years attending early infant diagnosis clinics in Jinja District, Eastern Uganda
(Makerere university, 2022)
Introduction: Globally, approximately 37 million people are living with Human Immunodeficiency Virus /Acquired Immune Deficiency Syndrome. About 92% of pregnant women living with HIV are in Sub-Saharan Africa. In Uganda, ...
Microbial characteristics of dental caries in HIV positive individuals
(2022)
Background: Dental caries is a multifactorial disease that affects many people. Even though microorganisms play a crucial role in causing dental caries, diagnosis is routinely macroscopic. In order to improve early detection ...