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Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: A prospective cohort study
(PLoS Medicine, 2010)
Background: Although antiretroviral therapy (ART) improves survival in persons with cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution inflammatory syndrome (IRIS), an exaggerated and ...
HIV/AIDS patients display lower relative bioavailability of Efavirenz than healthy subjects
(Adis Data Information BV., 2011)
Background: Pharmacokinetic studies of antiretroviral drugs are often conducted in adult healthy subjects, and the results are extrapolated to HIV/AIDS patients. HIV/AIDS, however, is known to cause morphological and ...
Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
(Lippincott Wilkins & Williams, 2011)
Background: Tuberculosis-HIV (TB-HIV) coinfection remains an
important cause of mortality in antiretroviral therapy (ART)
programs. In a cohort of TB-HIV–coinfected patients starting
ART, we examined the incidence and ...
Quantitative assessment of the sensitivity of various commercial reverse transcriptases based on armored HIV RNA
(Public Library of Science, 2010)
Background: The in-vitro reverse transcription of RNA to its complementary DNA, catalyzed by the enzyme reverse transcriptase, is
the most fundamental step in the quantitative RNA detection in genomic studies. As such, ...
Prevalence of HIV/AIDS among breast cancer patients and the clinico-pathological presentation of breast cancer with HIV/AIDS in Mulago Hospital
(Makerere University, 2011-04)
Background: Breast cancer is the most common site-specific cancer accounting for 33% of all female cancers and is responsible for 20% of the cancer-related deaths in women.
Objective: To determine the prevalence of HIV ...
Factors associated with male involvement in prevention of mother to child transmission of HIV (PMTCT) programmes in Entebbe Municipality
(Makerere University, 2012)
Background: Involving men in PMTCT programmes increases its uptake by women. Despite this observation, providers and implementers of PMTCT programmes continue to face challenges in reaching sexual partners of HIV positive ...
Non-linear mixed effects modeling of liver function biomarkers in TB-HIV patients co-treated with Rifampicin and Efavirenz based regimens
(2013-11)
Introduction
Survival has improved as a result of improved HIV therapy but liver disease remains a critical problem in HIV patients. HIV disease, ART and Tuberculosis treatments have all been documented to cause liver ...
Monocyte activation and dysregulation in treated and untreated hiv-1 infected Ugandans.
(Makerere University, 2018-08-30)
Introduction: Mechanism for increased non-AIDs co morbidities in HIV-1infected individuals on combinatorial antiretroviral therapy (cART) still requires exploration. This is majorly attributed to chronic monocyte activation ...
Prevalence and factors associated with use of traditional medicine among HIV positive clients in Mubende District, Uganda
(2012-03)
Introduction: Traditional Medicine is widely used in Uganda and Sub-Saharan African in general.There are proven adverse interactions between some herbal medications and ARV drugs hence the practice of concurrent use of the ...
Breastfeeding practice and associated factors among infants 1-11 months born to HIV positive mothers attending postnatal care at Nsambya Hospital
(Makerere University, 2017-01)
Introduction:
Breastfeeding practice significantly reduces the risk of malnutrition and infectious diseases especially in the first year of life. Although the HIV pandemic has hindered breastfeeding, WHO recommends it ...