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Steady state bioequivalence of generic and innovator formulations of stavudine, lamivudine, and nevirapine in HIV-infected Ugandan adults
(Public Library of Science, 2008-12-19)
Background: Generic antiretroviral therapy is the mainstay of HIV treatment in resource-limited settings, yet there is little evidence confirming the bioequivalence of generic and brand name formulations. We compared the ...
A case report: Harpes zooster IRIS in pregnancy
(African Health Sciences, 2009)
Pregnant women are increasingly being initiated on antiretroviral therapy either as part of prevention of mother to child transmission of HIV or as purely highly active antiretroviral therapy. In this case report, we ...
Voices on adherence to ART in Ethiopia and Uganda: a matter of choice or simply not an option
(Routledge - Taylor & Francis, 2009)
This paper explores HIV patients’ adherence to antiretroviral treatment (ART) in resource-limited contexts in Uganda and Ethiopia, where ART is provided free of charge. Qualitative semi-structured interviews were conducted ...
The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda
(Makerere University Medical School, 2008-03)
Background: Liver diseases are common in patients with HIV due to viral hepatitis B and C co-infections, opportunistic infections or malignancies, antiretroviral drugs and drugs for opportunistic infections. Objective: To ...
Steady-state pharmacokinetic comparison of generic and branded formulations of stavudine, lamivudine and nevirapine in HIV-infected Ugandan adults
(Oxford University Press, 2008-07-19)
Background: We aimed to compare the steady-state pharmacokinetic parameters and tolerability of Triomune 40w (stavudine 40 mg, lamivudine 150 mg and nevirapine 200 mg) and branded formulations of these drugs in HIV-infected ...
Longitudinal antiretroviral adherence in HIV+ Ugandan parents and their children initiating HAART in the MTCT-plus family treatment model: role of depression in declining adherence over time.
(Springer, 2009-03-20)
We conducted a study to assess the effect of family-based treatment on adherence amongst HIV-infected parents and their HIV-infected children attending the Mother-To-Child-Transmission Plus program in Kampala, Uganda. ...
Total lymphocyte count of 1200 is not a sensitive predictor of CD4 lymphocyte count among patients with HIV disease in Kampala, Uganda
(Makerere University Medical School, 2004-08)
Introduction: Total Lymphocyte Count (TLC) has been found to be an inexpensive and useful marker for staging disease, predicting progression to AIDS and death and monitoring response to ART. However, the correlation between ...
The liver in HIV in Africa
(International Medical Press, 2005)
As access to antiretroviral therapy improves across the African continent, liver disease is emerging as an important cause of morbidity and mortality among HIV-infected individuals. Although coinfection with hepatitis B ...
Blood cell picture in HIV patients in Uganda: a comparative study of the picture in HIV patients on highly active antiretroviral therapy with those who are not
(Makerere University, 2004-01)
Atleast 40 million people were infected with HIV World wide by the end of 2001, 90% of whom live in the developing countries. Less than 5% of these were able to access drugs that suppress the HIV Virus (ARVs) by the end ...
Factors influencing Kaposi's Sarcoma treatment outcome at Uganda Cancer Institute
(2008-07)
Uganda commonly diagnoses epidemic as well as endemic Kaposi's sarcoma cancer variants. A retrospective chart review of 1,483 Kaposi's sarcoma patient files for patients managed at Uganda Cancer institute in Mulago Referral ...