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Describing the nasopharyngeal microbiota of covid-19 patients in Uganda using next generation metagenomic sequencing and machine learning approaches
(Makerere University, 2023-11)
Background: While COVID-19 spread globally, the role of respiratory co-infections in patient outcomes and their prevalence has remained an area of exploration. Prior findings suggest a dominance of bacterial co-infections, ...
Employing whole genome sequencing to elucidate the pathogenic and Antimicrobial resistance potential of Klebsiella Oxytoca clinical isolates from Mulago Referral National Hospital in Uganda
(Makerere University, 2023-11-13)
Introduction: Klebsiella oxytoca (K. oxytoca) comprises a complex of related Gram negative opportunistic bacterial pathogens with scantly explored emerging antimicrobial resistance globally. Evidence shows shared virulence ...
Anatomical Variations of Gall bladder and Bile ducts-An MRI study
(Makerere University, 2023-11-04)
Introduction: The Anatomy of the biliary tree is complex and is characterized by the frequent presence of Anatomical variations which can be found in ~50% of the general population. Accurate knowledge of the bile duct ...
Genetic determinants of differential susceptibility to hepatitis B Infection among a general population cohort from southwestern Uganda: a genome-wide association study
(Makerere University, 2023-11)
Introduction: Hepatitis B is one of the major causes of mortality and morbidity worldwide. Hepatitis B infection causes liver inflammation and damage that may progress to liver cirrhosis, liver cancer and ultimately lead ...
HLA Class I and Pediatric HIV disease progression in Botswana and Uganda
(Makerere University, 2023)
Sub-Saharan Africa remains the global epicenter of the HIV epidemic; more than 70% (25 million) of all people living with HIV/AIDS are in Africa. To end the global epidemic, finding an effective HIV vaccine remains a top ...
Molecular identification of fungal species associted with Mycetoma in Uganda.
(Makerere University, 2023-12-12)
Background: Designated by the World Health Organization (WHO) as a neglected tropical disease (NTD), mycetoma is a chronic subcutaneous fungal and bacterial disease which causes profound morbidity. Mycetoma is mostly not ...
Stakeholders’ knowledge, perspectives and willingness to donate solid organs and associated ethical concerns in Uganda: a case study of Kampala
(Makerere University, 2023-11)
Background The demand for human organs globally is higher than the supply. The government has enacted The Uganda Human Organ Donation and Transplant Act, 2022 aimed at regulating organ donation and transplant activities. ...
Mycobacterium tuberculosis associated immune activation, inhibition and exhaustion profiling to predict active tuberculosis disease among presumptive tuberculosis participants and monitor anti-tuberculosis treatment response.
(Makerere University, 2023)
Globally, tuberculosis (TB) is the leading cause of mortality and morbidity especially among resource-limited populations including Uganda. This statistic is greatly fueled by the delay in diagnosis of the disease and ...
Awareness and perception of patients rights in clinical services among clients attending the outpatients department at Mawenzi Regional Referral Hospital, Tanzania
(Makerere University, 2023-10)
Background: Patient rights are those owed to the patient as a human being, by physicians, healthcare workers, and by the state. Without the appropriate understanding of the patient’s rights, the healthcare team may at times ...
The ethicality of mandatory COVID-19 vaccinations in Uganda: A qualitative study
(Makerere University, 2023-10)
Background: COVID-19 spread globally and caused greater than 3.9 million deaths worldwide. Approximately 2.8 billion doses of COVID-19 vaccines were administered worldwide. Some studies suggested that vaccination was the ...